Last update: Aug. 30, 2018
Very unsafe. Contraindicated.
Use of an alternative or cessation of breastfeeding.
A synthetic steroid with antigonadotropic and antiestrogenic activity due to the suppression of the pituitary gland’s gonadotropic hormone and with androgenic effects (Sanofi 2017, AEMPS 2017).
Used to treat endometriosis, fibrocystic breast disease, hereditary angioedema, mastalgia, premenstrual syndrome and menorrhagia.
Administration orally twice a day.
Since the last update we have not found published data on its excretion in breastmilk or its effect on breastfed infants (Briggs 2017).
In the absence of data regarding protein binding and the volume of distribution, the known pharmacokinetic data (low molecular weight, high pKa and prolonged half-life) make it likely that it would transfer to milk in amounts which could be significant.
Due to its possible androgenic effect on the infant and inhibition of prolactin, it should be avoided during breastfeeding (Hale 2019 p193, Sanofi 2017, AEMPS 2017).
We do not have alternatives for Даназол.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
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