Last update: May 22, 2021
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Oral dosage twice daily.
Low excreted into breast milk (Reece-Stremtan 2017, Østensen 2007, Jamali 1982). However, somnolence in 10% of breastfed infants has been reported (Ito 1993).
A case of acute anemia due to hemorrhage by coagulation disturbance in an one week aged infant (Fidalgo 1989).
Long-term use while breastfeeding (Davanzo 2014, Sachs 2013) or in case of newborn jaundice is not recommended because a competitive effect on liver metabolism has been shown (Risser 2009, Janssen 2000).
Short-term (1 week) or sporadic use has a low risk (Jamali 1982).
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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