Last update: July 31, 2018
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid is Nalidixic Acid in Chemical name.
Is written in other languages:1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid belongs to this group or family:
Main tradenames from several countries containing 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid in its composition:
Write to us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
An antibacterial quinolone used in the treatment of urinary tract infections.
Oral administration 4 times a day.
Its use is authorized in infants from 3 months of age (Sanofi 2008).
It is excreted in breastmilk in clinically insignificant amounts (Traeger 1980), much lower than the dose used in infants.
Hemolysis has been observed in a newborn whose breastfeeding mother was taking nalidixic acid (Chin 2001 --> Belton 1965).
Until there is more published data on this drug in relation to breastfeeding, safer known alternatives may be preferable, especially during the neonatal period and in case of prematurity or glucose-6-phosphate dehydrogenase deficiency (WHO 2002).
The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to alteration of the intestinal flora (Ito 1993).
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).