Last update: May 14, 2018


Very Low Risk for breastfeeding

Safe. Compatible.
Minimal risk for breastfeeding and infant.

Breast feeding protect from migraine recurrence during postpartum: migraine recurred within the first postpartum month in 100% of women who bottle-fed and in only 43.2% of those who breastfed.

While breastfeeding avoid using associations of drugs and those derived from phenazone, ergotamine, barbiturates or sedative medication.

Ibuprofen and Paracetamol (Acetaminophen) are safe, alone or associated to low doses of codeine or caffeine. Metamizole (Dipyrone) is widely used in Europe and Latin America without serious side effects. Among Triptan-type drugs Sumatriptan is a more convenient medication.

For prophylaxis purposes Propanolol, several anti-epileptic (Gabapentin, Valproate) and anti-depressant drugs (Verapamil, Amitriptylin). compatible.

See below the information of these related products:

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Migraine is also known as


  1. Burch R. Epidemiology and Treatment of Menstrual Migraine and Migraine During Pregnancy and Lactation: A Narrative Review. Headache. 2020 Jan;60(1):200-216. Abstract
  2. Burch R. Headache in Pregnancy and the Puerperium. Neurol Clin. 2019 Feb;37(1):31-51. Abstract
  3. VanderPluym J. Cluster Headache: Special Considerations for Treatment of Female Patients of Reproductive Age and Pediatric Patients. Curr Neurol Neurosci Rep. 2016 Abstract
  4. Wells RE, Turner DP, Lee M, Bishop L, Strauss L. Managing Migraine During Pregnancy and Lactation. Curr Neurol Neurosci Rep. 2016 Abstract
  5. Bordini CA, Roesler C, Carvalho Dde S, Macedo DD, Piovesan É, Melhado EM, Dach F, Kowacs F, Silva Júnior HM, Souza JA, Maciel JA Jr, Carvalho JJ, Speciali JG, Barea LM, Queiroz LP, Ciciarelli MC, Valença MM, Lima MM, Vincent MB. Recommendations for the treatment of migraine attacks - a Brazilian consensus. Arq Neuropsiquiatr. 2016 Abstract Full text (link to original source) Full text (in our servers)
  6. Amundsen S, Nordeng H, Nezvalová-Henriksen K, Stovner LJ, Spigset O. Pharmacological treatment of migraine during pregnancy and breastfeeding. Nat Rev Neurol. 2015 Apr;11(4):209-19. Review. Abstract
  7. Davanzo R, Bua J, Paloni G, Facchina G. Breastfeeding and migraine drugs. Eur J Clin Pharmacol. 2014 Abstract
  8. MacGregor EA. Migraine in pregnancy and lactation. Neurol Sci. 2014 Abstract
  9. Hutchinson S, Marmura MJ, Calhoun A, Lucas S, Silberstein S, Peterlin BL. Use of common migraine treatments in breast-feeding women: a summary of recommendations. Headache. 2013 Abstract Full text (link to original source) Full text (in our servers)
  10. Worthington I, Pringsheim T, Gawel MJ, Gladstone J, Cooper P, Dilli E, Aube M, Leroux E, Becker WJ; Canadian Headache Society Acute Migraine Treatment Guideline Development Group. Canadian Headache Society Guideline: acute drug therapy for migraine headache. Can J Neurol Sci. 2013 Sep;40(5 Suppl 3):S1-S80. Review. Abstract Full text (in our servers)
  11. Pringsheim T, Davenport W, Mackie G, Worthington I, Aubé M, Christie SN, Gladstone J, Becker WJ; Canadian Headache Society Prophylactic Guidelines Development Group. Canadian Headache Society guideline for migraine prophylaxis. Can J Neurol Sci. 2012 Abstract Full text (in our servers)
  12. Duong S, Bozzo P, Nordeng H, Einarson A. Safety of triptans for migraine headaches during pregnancy and breastfeeding. Can Fam Physician. 2010 Abstract Full text (link to original source) Full text (in our servers)
  13. Jürgens TP, Schaefer C, May A. Treatment of cluster headache in pregnancy and lactation. Cephalalgia. 2009 Abstract
  14. Marcus DA. Managing headache during pregnancy and lactation. Expert Rev Neurother. 2008 Abstract
  15. Raña-Martínez N. Migraña en la mujer. [Migraine in females]. Rev Neurol. 2008 Abstract
  16. Beseler-Soto B, Paricio-Talayero JM, Sánchez-Palomares M, Benlloch-Muncharaz M, Santos-Serrano L, Landa-Rivera L. MIgraña en la mujer. [Migraine and female]. Rev Neurol. 2008 Abstract
  17. MacGregor EA. Migraine in pregnancy and lactation: a clinical review. J Fam Plann Reprod Health Care. 2007 Abstract Full text (in our servers)
  18. Loder E. Migraine in pregnancy. Semin Neurol. 2007 Abstract
  19. Sances G, Granella F, Nappi RE, Fignon A, Ghiotto N, Polatti F, Nappi G. Course of migraine during pregnancy and postpartum: a prospective study. Cephalalgia. 2003 Abstract
  20. Allais G, Bosio A, Mana O, Airola G, Ciochetto D, Terzi MG, De Lorenzo C, Quirico PE, Benedetto C. [Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. Minerva Med. 2003 Abstract
  21. Moretti ME, Lee A, Ito S. Which drugs are contraindicated during breastfeeding? Practice guidelines. Can Fam Physician. 2000 Sep;46:1753-7. Review. Abstract Full text (link to original source) Full text (in our servers)
  22. Wojnar-Horton RE, Hackett LP, Yapp P, Dusci LJ, Paech M, Ilett KF. Distribution and excretion of sumatriptan in human milk. Br J Clin Pharmacol. 1996 Abstract Full text (link to original source) Full text (in our servers)
  23. Silberstein SD. Headaches and women: treatment of the pregnant and lactating migraineur. Headache. 1993 Abstract

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