Last update: March 2, 2018
Minimal risk for breastfeeding and infant.
Non-steroidal anti-inflammatory drug (NSAID) structurally related to indometacin, with less anti-inflammatory effect than other NSAIDs.
Oral or intravenous administration every 6 hours.
Excretion into breast milk is insignificant (Wischnik 1989).
Authorized use in neonates from 21 days (Martin 2017, Cohen 2011, Aldrink 2011, Papacci 2004).
Various medical societies and expert consensus consider the use of this medication safe during breastfeeding (Reece 2017, Worthington 2013, Østensen 2007, Lee 1993) although most recommend limited dosage and duration and oral administration.
Since the possibility of harmful effects on the blood and kidney among treated patients is controversial (not through breast milk) high dosing would better be avoided within 21 days post delivery (Reece 2017, Worthington 2013).
Keratolac eye drops are very safe because a low content of drug.
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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