Last update July 17, 2022
Likely Compatibility
We do not have alternatives for 茚达特罗.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
茚达特罗 is Indacaterol in Chinese.
Is written in other languages:茚达特罗 is also known as
Main tradenames from several countries containing 茚达特罗 in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | inhal: 45; oral 23 | % |
Molecular weight | 393 | daltons |
Protein Binding | 95 | % |
VD | 36.5 | l/Kg |
pKa | 8.51 | - |
T½ | 40 - 56 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Indacaterol is an inhaled long-acting beta2 adrenergic agonist used as a bronchodilator in the maintenance treatment of chronic obstructive pulmonary disease and moderate to severe asthma. Inhaled administration once daily.
Since the last update we have not found published data on its excretion in breastmilk.
Its pharmacokinetic data (very high percentage of protein binding and very wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.
Terbutaline which is a compound closely related to Formoterol is excreted into breast milk in non-significant amount. Salmeterol, another compound with similar characteristics, is also non-significantly excreted.
Its low oral bioavailability would hamper the pass to the infant’s plasma through the breastmilk ingested.
Several medical societies, experts authors and expert consensus consider the use of inhaled bronchodilators to be safe during breastfeeding. (Amir 2011, National Asthma 2004, Nelson 2001, Ellsworth 1994).