Last update Jan. 30, 2021

Terbutaline Sulfate

Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Short-acting beta-adrenergic bronchodilator, similar in characteristics to salbutamol.
Indicated in the treatment of asthma.
Administration preferably inhaled (also oral or intravenous).

It is excreted into breast milk in clinically non-significant amount (Lindberg 1984, Lonnerholm 1982, Boreus 1982) and neither clinical nor development problems were observed in infants whose mothers were treated with oral terbutaline (Lindberg 1984, Lonnerholm 1982, Boreus 1982) .
Plasma levels of these infants were undetectable or very low (Lindberg 1984, Lonnerholm 1982).

Preferable preparations are inhaled bronchodilators since <10% of the dose is absorbed.

Several medical societies, experts authors and expert consensus consider the use of inhaled bronchodilators to be safe during breastfeeding (Hale, Lactmed, Amir 2011, National Asthma 2004, Nelson 2001, Ellsworth 1994).
American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).

Alternatives

We do not have alternatives for Terbutaline Sulfate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Terbutaline Sulfate in other languages or writings:

Tradenames

Main tradenames from several countries containing Terbutaline Sulfate in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 30-50 (Inhal: 10) %
Molecular weight 549 daltons
Protein Binding 20 %
VD 1 - 2 l/Kg
pKa 8,86 -
Tmax 0,5 hours
T1/2 12 hours
M/P ratio 2 - 2,9 -
Theoretical Dose 0,0005 mg/Kg/d
Relative Dose 0,2 %
Ped.Relat.Dose 0,3 %

Total visits

14,419

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