Last update July 3, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Вилазодон is Vilazodone in Cyrillic.
Is written in other languages:Вилазодон belongs to these groups or families:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 50 - 72 | % |
Molecular weight | 442 | daltons |
Protein Binding | 96 - 99 | % |
VD | 4 - 8 | l/Kg |
pKa | 14.19 | - |
Tmax | 4 - 5 | hours |
T½ | 25 - 29 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Vilazodone is a selective serotonin reuptake inhibitor and a partial serotonin receptor agonist. Indicated in the treatment of depression. Oral administration once daily. Absorption is enhanced if taken with food.
At latest update no published data on excretion into breast milk were found.
Its pharmacokinetic data (very high percentage of protein binding, moderately high molecular weight and very wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.
Until more published data regarding breastfeeding is available, the use of a known and safer alternative drug should be preferred, especially during the neonatal period and/or in case of premature infant.
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