Last update July 3, 2022

فيلازودون

Likely Compatibility

Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.

Vilazodone is a selective serotonin reuptake inhibitor and a partial serotonin receptor agonist. Indicated in the treatment of depression. Oral administration once daily. Absorption is enhanced if taken with food.

At latest update no published data on excretion into breast milk were found.

Its pharmacokinetic data (very high percentage of protein binding, moderately high molecular weight and very wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.

Until more published data regarding breastfeeding is available, the use of a known and safer alternative drug should be preferred, especially during the neonatal period and/or in case of premature infant.

 


See below the information of this related product:

  • Maternal Depression (Fairly safe. Mild or unlikely adverse effects. Compatible under certain circumstances. Follow-up recommended. Read Commentary.)

Alternatives

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

فيلازودون is Vilazodone in Arabic.

Is written in other languages:

Groups

فيلازودون belongs to these groups or families:

Tradenames

Main tradenames from several countries containing فيلازودون in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 50 - 72 %
Molecular weight 442 daltons
Protein Binding 96 - 99 %
VD 4 - 8 l/Kg
pKa 14.19 -
Tmax 4 - 5 hours
25 - 29 hours

References

  1. Forest. Vilazodone. Drug Summary. 2015 Full text (link to original source) Full text (in our servers)

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