Last update Nov. 27, 2019
Very Low Risk
It is a reuptake-inhibitor of Serotonin and Norepinephrine, and a precursor of Desvenlafaxine.
Oral administration one to three times a day
Excreted into breast milk in amounts that may be clinically significant (Pogliani 2019, Schoretsanitis 2018, Rampono 2011, Newport 2009, Misri 2006, Koren 2006, Berle 2004, Ilett 2002), which has been found in the plasma of breastfed infants from treated mothers (Rampono 211, Newport 2009, Berle 2004, Weissman 2004, Hendrick 2001, Ilett 2002 y 1998).
However, side-effects in those infants have not been shown.
Various studies failed to show short or long-term side-effects among infants whose mothers were on Venlafaxine, both on physical or psychomotor development (Pogliani 2019, Rampono 2011, Newport 2009, Misri 2006, Berle 2004, Hendrick 2003 y 2001, Ilett 2002 y 1998).
It may induce galactorrhea (Camkurt 2017, Ashton 2007, Pae 2004).
The poor extrauterine adaptation that may appear in neonates just after birth when the pregnant woman has been treated with selective reuptake-inhibitors of Serotonin like Venlafaxine or Mirtazapine (Hale 2010), is seen to be mild if the baby is breastfed (Kieviet 2013, Lanza 2009). In the case report of a mother who was taking this medication during pregnancy, her infant had shown amelioration of symptoms due to Abstinence Syndrome after having been breastfed (Boucher 2009, Koren 2006).
Various medical societies and expert consensus consider the use of this medication safe during breastfeeding (Hale 2019, Sriraman 2015, Rowe 2013, Berle 2011, Patil 2011, Schaefer 2007, Gjerdingen 2003).
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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