Last update June 29, 2022
Very Low Risk
Antidepressant Oral administration one to two times daily.
It is excreted into breast milk in clinically non-significant amount. (Saito 2021, Misri 2006, Verbeeck 1986)
Not effects on the infant's physical and psychomotor development at both short or long-term were found. (Saito 2021, Newport 2009, Misri 2006 y 1991)
Variable levels of Prolactin secretion (increment or lowering), which were non-significant, were found after the use of Trazodone (Otani 1995, Roccatagliata 1982 y 1979, Rolandi 1981, Mazzi 1979) . Trazodone can cause galactorrhea. (Arslan 2015)
Expert authors consider the use of this medication possible during breastfeeding. (Hale, LactMed, Uguz 2021)
Because there is less experience published than with other drugs of the same pharmacological group, it should be preferred the use of an alternative drug that is known to be safer in the neonatal period or prematurity.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM