Last update June 18, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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ثلاثي ميبرامين is Trimipramine in Arabic.
Is written in other languages:ثلاثي ميبرامين is also known as
ثلاثي ميبرامين belongs to these groups or families:
Main tradenames from several countries containing ثلاثي ميبرامين in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 41 | % |
Molecular weight | 294 | daltons |
Protein Binding | 95 | % |
Tmax | 2 - 3 | hours |
T½ | 11 - 25 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a tricyclic antidepressant with actions and uses similar to those of amitriptyline. It has marked antimuscarinic and sedative properties. It is used in the treatment of depression. Oral administration in one or two daily doses.
Since the last update we have not found published data on its excretion in breastmilk.
Its high percentage of protein binding, make it highly unlikely that significant quantities will pass into breast milk.
It can cause galactorrhea. (Wolfsperger 2005)
Somnolence and adequate feeding of the infant should be monitored. Because it can cause sedation and drowsiness, it is not recommended to share a bed (co-sleeping, bed-sharing) with the baby if this medication is being taken, due to increased risk of asphyxia or sudden infant death. (UNICEF 2018, 2017, 2014 and 2013, Landa 2012, ABM 2008, UNICEF 2006)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable (Sriraman 2015, Davanzo 2011, ABM 2008), especially during the neonatal period and in the event of prematurity.
Women suffering from depression during pregnancy need more breastfeeding support due to their increased risk of breastfeeding problems and early weaning. (Grzeskowiak 2018, Leggett 2017, Venkatesh 2017, Gorman 2012)
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