Last update June 29, 2022
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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νεφαζοδόνη υδροχλωρική is Nefazodone Hydrochloride in Greek.
Is written in other languages:νεφαζοδόνη υδροχλωρική belongs to these groups or families:
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is an antidepressant structurally related to trazodone. Oral administration in two daily doses.
Its pharmacokinetic data (high percentage of protein binding, large volume of distribution and moderately high molecular weight) explain the negligible passage into breast milk observed. (Yapp 2000, Dodd 2000 & 1999)
However, a 9-week-old, 27-week-premature infant whose mother was taking nefazodone had drowsiness, lethargy, growth retardation, and hypothermia. (Gjerdingen 2003, Yapp 2000)
Until more published data is known about this drug in relation to breastfeeding, known safer alternatives are preferable (Davanzo 2011), especially during the neonatal period and in the event of prematurity.
Withdrawn from market in many countries because an increased risk of a rather rare but severe hepatotoxicity. (Choi 2003)