Last update April 16, 2024
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Fosinopril sodium in other languages or writings:
Fosinopril sodium belongs to these groups or families:
Main tradenames from several countries containing Fosinopril sodium in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 36 | % |
Molecular weight | 586 | daltons |
Protein Binding | 95 | % |
pKa | 3.78 | - |
Tmax | 3 | hours |
T½ | 14 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Fosinopril and its active metabolite fosinoprilat are angiotensin converting enzyme inhibitors (ACEI) used in the treatment of hypertension and heart failure. Oral administration once day.
Except for a reference of the manufacturer (FDA 2002) with no declared values, since the last update we have not found published data on its excretion in breastmilk.
Other compounds in the same group (ACEI) are not significantly excreted in breast milk, but until further published data on this drug in relation to breastfeeding are known safer alternatives may be preferable. (Hale, LactMed, Anderson 2018)
Due to its potential renal toxicity in premature infants, it is preferable to avoid its use during the neonatal period in case of prematurity. (Serrano 2015)
The protective role of breastfeeding against maternal hypertension has been proven. (Park 2018)