Last update Oct. 9, 2016
Calcium-channel-blocking drug which is a piperazine derivative antihistamine with sedative effects.
Used in prophylaxis of migraines and dizziness.
At latest update no published data on excretion into breast milk were found.
It may increase prolactin level (from Cortelli Formisano 1985 to 1991).
Despite its high protein-binding capacity, because of a very long half-life span (18 days), there is a higher risk of excretion into breastmilk.
A known and safer alternative should be preferred until more published data on this drug related to breastfeeding is available, - e.g. Propranolol, Metoprolol, Sertraline, Escitalopram, Amitrptilina or Valproate for Migraine prophylaxis (Pringsheim 2012, Davanzo 2014) and Nimodipine, Betahistine or Ginkgo biloba for vertigo prophylaxis, especially in the neonatal period and in case of prematurity.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.