Last update Sept. 30, 2014


Very Low Risk

Safe. Compatible. Minimal risk for breastfeeding and infant.

Excreted into breast milk in a non-significant amount.

Because of pharmacokinetic data (high protein-binding capacity and low oral bioavailability) the observed low excretion into breast milk would be explained.

Nimodipine does not alter secretion of Prolactin.


We do not have alternatives for Nimodipine since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Nimodipine belongs to this group or family:


Variable Value Unit
Oral Bioavail. 3 - 13 %
Molecular weight 418 daltons
Protein Binding 97 - 99 %
VD 0.94 l/Kg
Tmax 10.6 - 1.6 hours
1.1 - 1.7 hours
M/P ratio 0.06 - 0.3 -
Theoretical Dose 0.00024 mg/Kg/d
Relative Dose 0.004 %


  1. Malachias MV, Figueiredo CE, Sass N, Antonello IC, Torloni MR, Bortolotto MRF L. 7th Brazilian Guideline of Arterial Hypertension: Chapter 9 - Arterial Hypertension in pregnancy Arq Bras Cardiol. 2016 Abstract Full text (link to original source) Full text (in our servers)
  2. Bayer. Nimodipine. Drug Summary. 2011 Full text (in our servers)
  3. MS-AgEspMedyPS. Nimodipino. Ficha técnica. 2004 Full text (in our servers)
  4. Carcas AJ, Abad-Santos F, de Rosendo JM, Frias J. Nimodipine transfer into human breast milk and cerebrospinal fluid. Ann Pharmacother. 1996 Abstract
  5. Tonks AM. Nimodipine levels in breast milk. Aust N Z J Surg. 1995 Abstract
  6. Formisano R, Falaschi P, Cerbo R, Proietti A, Catarci T, D'Urso R, Roberti C, Aloise V, Chiarotti F, Agnoli A. Nimodipine in migraine: clinical efficacy and endocrinological effects. Eur J Clin Pharmacol. 1991 Abstract
  7. Haitas B, Joffe BI, Edelstein D, Panz V, Lamprey JM, Seftel HC. Calcium antagonists (nifedipine and nimodipine) and pituitary responses to thyrotropin releasing hormone stimulation. J Cardiovasc Pharmacol. 1986 Abstract

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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain

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