Last update May 11, 2019
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C02AC02 is Guanfacine Hydrochloride in ATC Code/s.Is written in other languages:
C02AC02 belongs to this group or family:
Main tradenames from several countries containing C02AC02 in its composition:
|Tmax||1 - 5||hours|
|T½||17 (10 - 30)||hours|
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Central action alpha-1 adrenergic blocker with indications similar to clonidine, used in the treatment of hypertension and attention deficit hyperactivity disorder.
Oral administration once a day.
Since the last update we have not found any published data on its excretion in breast milk.
Its pharmacokinetic data (low molecular weight, low protein binding and prolonged half-life) make it likely that it would pass into breast milk in amounts which could be significant.
It can reduce prolactin levels (Hauger 1981), but when lactation is well established, milk production does not depend so much on prolactin levels.
Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug may be used (Anderson 2018, Schaefer 2007 p685), especially during the neonatal period and/or in case of premature infants.