Last update Aug. 20, 2022
Very Low Risk
It is a dihydropyridine calcium channel blocker, peripheral and coronary vasodilator, indicated for the treatment of angina pectoris and hypertension. Oral administration once or twice daily.
It is excreted into breast milk in non-significant amount (Malfará 2019, Taddio 1996, Manninen 1991, Ehrenkranz 1989, Penny 1989) with no problems among breastfed infants whose mothers were treated with this medication. (Wu 2012, O'Sullivan 2011, Page 2006, Anderson 2004, Garrison 2002, Lawlor 1997, Penny 1989)
No alteration on breast milk composition or production has been seen. (Magee 2005)
Shown to be effective at a dose of 10 - 20 mg three times-a-day for pain relief related to Raynaud phenomenon of the nipple. (Di Como 2020, Barrett 2013, Anderson 2004, Garrison 2002)
Possible side effects (headache, hypotension) in the mother should be monitored. Gynecomastia may occur with the use of nifedipine and other calcium channel blockers. (Deepinder 2012, Tanner 1988)
Several medical societies, experts and expert consensus, consider the use of this medication to be safe or very probably safe during breastfeeding (Hale, LactMed, Malachias 2016, Briggs 2015, Schaefer 2015, Serrano 2015, Rowe 2013, Dennis 2012, Chen 2010, Ghanem 2008). American Academy of Pediatrics 2001: Maternal Medication Usually Compatible With Breastfeeding. (AAP 2001). Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding. (WHO 2002)
We do not have alternatives for Nifedipine since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Asociación Pro Lactancia Materna (APROLAM) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM