Last update: July 31, 2018

Sweetleaf, Sweet leaf

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

From the leaves of the Stevia rebaudiana plant originating in Paraguay several glycosides are obtained (rebaudiosides A, B, C, D and E, stevioside and dulcoside) which are used as a substitute for sugar.
The different glycosides are metabolized to steviol (Purkayastha 2016, Wheeler 2008).
It is a non-caloric sweetener, around 300 times sweeter than sucrose (Vargas 2012).

It has been commonly used in South America for centuries and in Japan and China for decades. It is used in traditional medicine with no proven scientific data on its effect on hypertension or hyperglycemia (Ulbricht 2010).

Devoid of toxicity (Gens 2003) at the dose of one or two cups of infusion daily. Maximum intake of steviol: 4 mg per Kg of weight per day.

Steviol glycosides are not genotoxic or carcinogenic (Urban 2013).

Since the last update we have not found published data on its excretion in breastmilk.

Given its lack of toxicity at correct doses, moderate consumption would be compatible with breastfeeding.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Sweetleaf, Sweet leaf is also known as Stevioside. Here it is a list of alternative known names::


Sweetleaf, Sweet leaf in other languages or writings:

Groups

Sweetleaf, Sweet leaf belongs to these groups or families:

Pharmacokinetics

Variable Value Unit
Molecular weight 805 daltons
Tmax 8 - 12 hours
T1/2 14 hours

References

  1. Purkayastha S, Markosyan A, Prakash I, Bhusari S, Pugh G Jr, Lynch B, Roberts A. Steviol glycosides in purified stevia leaf extract sharing the same metabolic fate. Regul Toxicol Pharmacol. 2016 Abstract
  2. MedlinePlus. Edulcorantes y sustitutos del azúcar. Información de salud para usted. 2015 Full text (link to original source) Full text (in our servers)
  3. MedlinePlus. Sweeteners - sugar substitutes Trusted Health Information for you. 2015 Full text (link to original source) Full text (in our servers)
  4. Urban JD, Carakostas MC, Brusick DJ. Steviol glycoside safety: is the genotoxicity database sufficient? Food Chem Toxicol. 2013 Abstract
  5. Vargas Corrales, Verónica. Elaboración de té aromático a base de plantas cedrón (aloysia citrodora) y toronjil (mellisa officinalis) procesado con stevia (stevia rebaudiana bertoni) endulzante natural, utilizando el método de deshidratación. Tesis doctoral. Universidad Técnica de Cotopaxi. 2012 Full text (link to original source) Full text (in our servers)
  6. Ulbricht C, Isaac R, Milkin T, Poole EA, Rusie E, Grimes Serrano JM, Weissner W, Windsor RC, Woods J. An evidence-based systematic review of stevia by the Natural Standard Research Collaboration. Cardiovasc Hematol Agents Med Chem. 2010 Abstract
  7. Wheeler A, Boileau AC, Winkler PC, Compton JC, Prakash I, Jiang X, Mandarino DA. Pharmacokinetics of rebaudioside A and stevioside after single oral doses in healthy men. Food Chem Toxicol. 2008 Abstract
  8. Geuns JM. Stevioside. Phytochemistry. 2003 Abstract

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