Last update: Nov. 29, 2019


Low Risk for breastfeeding

Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Sulfonamide with properties similar to those of sulfamethoxazole.
Used topically (dermatological and vaginal) for the treatment of susceptible infections.

Since the last update we have not found any published data on its excretion in breast milk.

The small dose and poor plasma uptake of most topical dermatological preparations make it very unlikely that significant amounts will pass into breast milk.
Vaginally it can be absorbed in variable quantity (PDR 2019). Do not use vaginally during the neonatal period and in deficit of glucose-6-phosphate dehydrogenase (AEHH2012).

Do not apply on nipple-areola so as to avoid its ingestion by the infant; alternatively clean before breastfeeding.

See below the information of this related product:


Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Sulfanilamide is also known as

Sulfanilamide in other languages or writings:


Main tradenames from several countries containing Sulfanilamide in its composition:


Variable Value Unit
Oral Bioavail. ≈ 0 %
Molecular weight 172 daltons


  1. PDR online Sulfanilamide (AVC Vaginal Cream 15%). Drug Summary. 2019 Full text (link to original source) Full text (in our servers)
  2. AEHH: Asociación Española de Hematología y Hemoterapia. EL DEFICIT DE GLUCOSA-6-FOSFATO DESHIDROGENASA (G6PD). EL FAVISMO AEHH 2012 Full text (link to original source) Full text (in our servers)

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e-lactancia is a resource recommended by La Liga de la Leche de México from Mexico

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