Last update: April 4, 2021

舒洛地昔

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Heparin-like glycosaminoglycan which is a mixture of low molecular weight heparin (80%) and dermatan sulfate (20%) that has hypolipaemic and antithrombotic properties and used for treatment of venous insufficiency.
It does not have significant effects on coagulation but some protective properties on vascular endothelium is attributed.

At latest update on excretion into breast milk no published data were found.

Pharmacokinetic data (large volume of distribution and high molecular weight) make it unlikely the passage into milk in significant amounts.

Until more published data about this drug regarding breastfeeding is available, a safer alternative should be used, especially during the neonatal period and in case of prematurity.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

舒洛地昔 is Sulodexide in Chinese.

Is written in other languages:

Group

舒洛地昔 belongs to this group or family:

Tradenames

Main tradenames from several countries containing 舒洛地昔 in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 40 (20 - 60) %
Molecular weight 6.500 (5.000 - 8.000) daltons
VD 1,0 ± 0,2 l/Kg
Tmax 1.33 ± 0.58 hours
T1/2 11,7 - 25,8 hours

References

  1. AEMPS. Sulodexida. Ficha técnica. 2014 Full text (in our servers)
  2. Coccheri S, Mannello F. Development and use of sulodexide in vascular diseases: implications for treatment. Drug Des Devel Ther. 2013 Abstract
  3. Harenberg J. Review of pharmacodynamics, pharmacokinetics, and therapeutic properties of sulodexide. Med Res Rev. 1998 Abstract

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