Last update: June 10, 2014
Poorly safe. Evaluate carefully.
Use safer alternative or interrupt breastfeeding 3 to 7 T ½ (elimination half-lives).
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Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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Main tradenames from several countries containing Oxycodone in its composition:
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e-lactancia is a resource recommended by La Liga de la Leche, España from Spain
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Very often used for treatment of pain associated to episiotomy or Cesarean section operation.
Excreted and accumulates into breast milk in significant amount along with associated problems among 20% of breastfed infants from treated mothers. Side effects have been rarely severe like excessive sedation, letargia, hypothermia and apnea. Dose should not be higher than 30 mg a day for no longer than 3 days.
Women with some variants of enzyme-linked gene CYP2D6 who are on Oxycodone and their breastfed infants may experience increased sedation. Dose should not be higher than 30 mg a day for no longer than 3 days.
Use of Oxycodone during childhood is risky because of a large elimination half-life variability.
Adequately use of nonsteroidal anti-inflammatory drugs (NSAIDs) may attain pain relief with less side effects than with narcotic analgesics.