Last update: Sept. 24, 2015

Flurbiprofen

Very Low Risk for breastfeeding


Safe. Compatible.
Not risky for breastfeeding or infant.

Non-steroidal analgesic drug with a similar chemical structure as Ibuprofen.

It is excreted into breast milk in non detectable or clinically non-significant amount.

Alternatives

We do not have alternatives for Flurbiprofen since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Flurbiprofen in other languages or writings:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 244 daltons
Protein Binding 99 %
VD 0,1 l/Kg
Tmax 1 - 2 hours
T1/2 3 - 6 hours
M/P ratio 0,03 -
Theoretical Dose 0,01 mg/Kg/d
Relative Dose 0,3 %

References

  1. Sachs HC; Committee On Drugs. The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796-809. Abstract Full text (link to original source) Full text (in our servers)
  2. Davies NM. Clinical pharmacokinetics of flurbiprofen and its enantiomers. Clin Pharmacokinet. 1995 Abstract
  3. Lee JJ, Rubin AP. Breast feeding and anaesthesia. Anaesthesia. 1993 Jul;48(7):616-25. Review. Abstract Full text (link to original source) Full text (in our servers)
  4. Smith IJ, Hinson JL, Johnson VA, Brown RD, Cook SM, Whitt RT, Wilson JT. Flurbiprofen in post-partum women: plasma and breast milk disposition. J Clin Pharmacol. 1989 Abstract
  5. Goldsmith DP. Neonatal rheumatic disorders. View of the pediatrician. Rheum Dis Clin North Am. 1989 Abstract
  6. Cox SR, Forbes KK. Excretion of flurbiprofen into breast milk. Pharmacotherapy. 1987 Abstract
  7. Needs CJ, Brooks PM. Antirheumatic medication during lactation. Br J Rheumatol. 1985 Abstract

Total visits

44,732

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at elactancia.org@gmail.com

e-lactancia is a resource recommended by El Parto Es Nuestro from Spain

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM