Last update: Oct. 15, 2014


Low Risk for breastfeeding

Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Histamine analogue drug which is used for treatment of Meniere's vertigo

At latest update, relevant information on excretion into breast milk was not found.

Because of pharmacokinetic data it is likely excretion into breast milk though from low plasma levels, usually below the detection threshold (100 pg/mL)

Side-effects likely would be mild: nausea, dyspepsia, head ache.

Consider other better known options, otherwise follow-up the child for symptoms like nausea, crying and fussiness.


Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 136 daltons
Protein Binding < 5% %
Tmax 1 hours
T1/2 3,5 hours


  1. Schaaf H. Cochrane analysis on betahistine omitted. Dtsch Arztebl Int. 2013 Abstract Full text (link to original source) Full text (in our servers)
  2. Monzani D, Barillari MR, Alicandri Ciufelli M, Aggazzotti Cavazza E, Neri V, Presutti L, Genovese E. Effect of a fixed combination of nimodipine and betahistine versus betahistine as monotherapy in the long-term treatment of Ménière's disease: a 10-year experience. Acta Otorhinolaryngol Ital. 2012 Abstract Full text (link to original source) Full text (in our servers)
  3. Betahistina. Ficha técnica. 2011 Full text (in our servers)
  4. Betahistine. Drug Summary. 2010 Full text (in our servers)
  5. Della Pepa C, Guidetti G, Eandi M. Betahistine in the treatment of vertiginous syndromes: a meta-analysis. Acta Otorhinolaryngol Ital. 2006 Abstract Full text (link to original source) Full text (in our servers)
  6. James AL, Burton MJ. Betahistine for Menière's disease or syndrome. Cochrane Database Syst Rev. (rev. 2011) 2001 Abstract Full text (link to original source) Full text (in our servers)

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