Last update: Aug. 17, 2019
Not risky for breastfeeding or infant.
Synthetic derivative of lactulose. It is a disaccharide analogue of lactulose with similar action and uses.
It does not hydrolyze in the intestine, so it is not absorbed, reaching the colon intact, where it exerts its function as an osmotic laxative (AEMPS 2015, Würsch 1989, Metzger 1988). Indicated in constipation and hepatic encephalopathy.
Oral administration in a daily dose.
Since the last update we have not found published data on its excretion in breastmilk.
Its virtually zero oral bioavailability makes plasma levels null and therefore does not transfer to breastmilk (AEMPS 2015, P-RMS 2010).
For the same reason, it impedes transfer from breastmilk to infant plasma.
We do not have alternatives for 4-O-(β-d-Galactopyranosyl)-d-glucitol since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child's Health in Greece
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM