Last update Aug. 11, 2024

Triaconazole

Compatible

Safe product and/or breastfeeding is the best option.

It is a triazole antifungal similar to fluconazole and itraconazole used in the local treatment of vulvovaginal candidiasis. Intravaginal administration as a cream or ovule for 3 to 7 nights.

Only a small amount (5-16%) is absorbed systemically, achieving very low plasma levels (6 ng/ml), so the amount excreted in milk is assumed to be negligible. (Hale).

In addition, its high percentage of protein binding makes it even less likely that significant amounts will pass into milk.

Alternatives

  • Clotrimazole (Safe product and/or breastfeeding is the best option.)
  • Fluconazole (Safe product and/or breastfeeding is the best option.)
  • Itraconazole (Safe product and/or breastfeeding is the best option.)
  • Miconazole (Safe product and/or breastfeeding is the best option.)

Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Triaconazole is also known as Terconazole.


Triaconazole in other languages or writings:

Group

Triaconazole belongs to this group or family:

Tradenames

Main tradenames from several countries containing Triaconazole in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 100 %
Molecular weight 533 daltons
Protein Binding 94.9 %
6.9 (4 - 11.3) hours

References

  1. Taro Ph. Terconazole. Drug Summary. 2015 Full text (in our servers)
  2. Mactal-Haaf C, Hoffman M, Kuchta A. Use of anti-infective agents during lactation, Part 3: Antivirals, antifungals, and urinary antiseptics. J Hum Lact. 2001 Abstract

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