Last update June 18, 2022
Very Low Risk
It is a selective serotonin and norepinephrine reuptake inhibitor antidepressant. Oral administration once a day.
Excreted into breast milk in clinically non-significant amount (Collin 2018, Andrade 2014, Rowe 2013, Boyce 2011, Berle 2011, Briggs 2009, EMA 2009, Lanza 2009, Lobo 2008) with no side-effects being observed in breastfed infants from treated mothers (Briggs 2009).
Plasma level in those infants was very low or undetectable (Boyce 2011, Briggs 2009).
Galactorrhea has been observed with or without an increase in prolactin (Derle 2021, Özkan 2020, Luo 2019, McGrane 2019, Demirci 2015, Belli 2013, Korkmaz 2011), but less frequently than with other antidepressants. (Trenque 2011)
Expert authors consider the use of this medication possible during breastfeeding. (Hale, Uguz 2021, Larsen 2015)
Because there is less experience published than with other antidepressants of the same pharmacological group, it should be preferred the use of an alternative drug that is known to be safer in the neonatal period or prematurity.
Women who use antidepressant medication during pregnancy are in need of more support for breastfeeding since they are at risk for early weaning (Leggett 2017).
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM