Last update June 26, 2022
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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كاريبرازين is Cariprazine Hydrochloride in Arabic.
Is written in other languages:كاريبرازين belongs to these groups or families:
Variable | Value | Unit |
---|---|---|
Molecular weight | 464 | daltons |
Protein Binding | 91 - 97 | % |
pKa | 15.68 | - |
Tmax | 3.6 (metab: 6 - 18) | hours |
T½ | 31 - 68. (metab: 30 - 446) | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
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Atypical or second-generation antipsychotic indicated for the treatment of schizophrenia and other psychotic disorders. Oral administration once daily.
Since the last update, we have not found any published data on its excretion in breastmilk.
Its high percentage of protein binding make it highly unlikely that significant quantities will pass into breast milk.
Cariprazine and its two active metabolites have a very long half-life (2 days, 3 weeks), which could favor the passage into breast milk.
Cariprazine produces minimal effects on prolactin levels. (Culpepper 2022)
Until there is further published data on this drug in relation to breastfeeding, known safer alternatives are preferable (Wichniak 2021), especially during the neonatal period and in cases of prematurity.
See below the information of this related product: