Last update Sept. 4, 2021
It is a stable analog of the prostaglandin epoprostenol (prostacyclin) with pharmacokinetics and vasodilator and antiplatelet properties similar to those of epoprostenol.
Used in peripheral vascular disorders and pulmonary hypertension.
Administration by intravenous infusion or by inhalation.
At the date of the last update we did not find any published data on its excretion in breast milk.
Its acid pKa and large volume of distribution, as well as its very fast elimination half-life (T½ of 15 - 30 minutes) make it unlikely to pass into breast milk in significant amount.
Its low oral bioavailability (Kirsten 1998) makes it difficult for the infant to pass into plasma from ingested breast milk.
No problems were reported in a newborn breastfed by a mother treated with iloprost (Mirdamadi 2016).
It is a medication that is used in newborns, including premature (Verma 2021, Eifinger 2008).
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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