Last update May 14, 2021
Very Low Risk
SSRI antidepressant with actions and uses similar to those of fluoxetine.
Oral administration once or twice daily.
It is excreted in breast milk in small amounts (Weisskopf 2017, Kristensen 2002, Arnold 2000, Hägg 2000, Yoshida 1997, Wright 1991). Serum levels of infants from breastfeeding mothers who were treated have been shown to be undetectable or very low (Kristensen 2002, Piontek 2001, Hendrick 2001) with some exception (Arnold 2000).
Although there are some isolated case of gastroenteritis (Uguz 2015), no short-term or long-term problems have been observed in the majority of infants whose mothers took it (Gentile 2006, Kristensen 2002, Hendrick 2003 y 2001, Arnold 2000, Yoshida 1997, Wright 1991).
Neonatal poor adaptation problems have not been observed during the immediate neonatal period, in term or preterm infants whose mothers took fluvoxamine during pregnancy (Kieviet 2015).
Galactorrhea associated or not to hyperprolactinemia, may appear (Chakladar 2020, Trenque 2011, Egberts 1997).
Several medical societies, experts and expert consensus, consider the use of this medication safe or probably safe during breastfeeding (Hale, Lactmed, Uguz 2021, Sriraman 2015, Orsolini 2015, Rowe 2013, Davanzo 2011, Berle 2011, Patil 2011, Lanza 2011, Gentile 2005, Rubin 2004, Gjerdingen 2003, Nordeng 2001).
Safer known alternatives may be preferable, especially during the neonatal period and in cases of prematurity (Weissman 2004).
Women suffering from depression during pregnancy need more breastfeeding support due to their increased risk of breastfeeding problems and early weaning (Grzeskowiak 2018, Leggett 2017, Venkatesh 2017, Gorman 2012).
Suggestions made at e-lactancia are done by APILAM team, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Confederación Nacional de Pediatría (CONAPEME) of Mexico
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM