Last update Feb. 1, 2024
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Flucytosine is also known as
Flucytosine in other languages or writings:
Flucytosine belongs to these groups or families:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 78 - 89 | % |
Molecular weight | 129 | daltons |
Protein Binding | 28 - 31 | % |
VD | 0.6 (0.4 - 0.8) | l/Kg |
pKa | 8.31 | - |
Tmax | 2 | hours |
T½ | 2.4 - 4.8 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Flucytosine is an antifungal indicated in combination with amphotericin B to treat severe systemic infections caused by Candida or Cryptococcus. Intravenous and oral administration.
At the time of the last update, we found no published data on its excretion in breast milk.
Although its low molecular weight and its low binding to plasma proteins facilitate its excretion in breast milk, its large volume of distribution would make it difficult.
It is a drug authorized for use in neonatology, even in premature infants. (Clerihew 2012)
If administered during lactation, the infant should be monitored for vomiting, diarrhea or skin rash.
The possibility of breastfeeding depends on the mother's clinical condition, which is not good when this medication is required. (Mactal 2001)