Last update Feb. 28, 2023
It is an antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. Intravenous and local topical administration (intestinal, gynecological).
On latest update relevant data on breastfeeding was not found.
Its pharmacokinetic data (very high percentage of protein binding, high molecular weight and wide volume of distribution) make it highly unlikely that significant quantities will pass into breast milk.
Its very low oral bioavailability minimizes the passage into plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.
Medication for pediatric use, even in newborns. (Auron 2009, Lilien 1978)
Expert authors consider the use of this medication to be safe or probably compatible during breastfeeding. (Hale, Briggs 2015, Schaefer 2015, Ilett 2005, Mactal 2001)
. (Hale, Briggs 2015, Schaefer 2015, Ilett 2005, Mactal 2001)
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2006 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM