Last update Oct. 12, 2022
Limited compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Фенилпропаноламин is Phenylpropanolamine; Phenylpropanolamine Hydrochloride in Cyrillic.
Is written in other languages:Фенилпропаноламин is also known as
Фенилпропаноламин belongs to these groups or families:
Main tradenames from several countries containing Фенилпропаноламин in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 38 | % |
Molecular weight | 188 | daltons |
Protein Binding | Low / Bajo | % |
VD | 4.5 | l/Kg |
pKa | 13.9 | - |
Tmax | 0.5 - 2 | hours |
T½ | 3.8 - 4.3 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a sympathomimetic with an action similar to ephedrine, used in products such as nasal decongestant and for weight loss. Oral administration twice daily.
On latest update relevant data on breastfeeding was not found.
Pharmacokinetic data indicates that drug excretion into breast milk may occur.
Appears as part of many compounds for cough relief, mucolytics, expectorants and nose decongestants. Single drug (one active principle only) medicines should be preferred mostly while breastfeeding.
Withheld from marketing in many countries because of hypertension and severe side effects. FDA withdrew it due to safety risks and lack of efficacy.
Until there is more published data on this drug in relation to breastfeeding, safer known alternatives are preferable, especially during the neonatal period and in case of prematurity.
There is good quality evidence that exclusive breastfeeding helps to regain pre-pregnancy weight earlier than if breastfeeding is partial (mixed) or there is no breastfeeding, and that prolonged breastfeeding helps maintain that loss and as well as body fat loss.(Jayasinghe 2021, Schalla 2017, López 2016, Jarlenski 2014, Sámano 2013, Neville 2014, Hatsu 2008, Dewey 2004, 2001 y 1993, Kramer 1993)