Last update Jan. 6, 2022
Psychostimulant precursor to amphetamine that is metabolized in the body to amphetamine (Cody 2002 and 2001) used as an anti-obesity medication. It can cause insomnia, anorexia, nervousness, and cardiomyopathy (Montastruc 2010, Cornaert 1986). Oral administration once a day.
Since the last update we have not found any published data on its excretion in breast milk.
The paucity of published pharmacokinetic data does not allow prediction of its excretion in human milk, but its metabolite amphetamine is excreted in human milk.
Due to its negative risk-benefit balance, it has been withdrawn from the market by the main drug agencies (EMA and FDA) of most countries in the world.(Onakpoya 2016, AEMPS 2000)
Breastfeeding women return to pre-pregnancy body weight sooner than bottle-feeding mothers.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it.
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