Last update Nov. 19, 2022
Likely Compatibility
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Caspofungine Acetate in other languages or writings:
Main tradenames from several countries containing Caspofungine Acetate in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | Baja - Poor | % |
Molecular weight | 1.213 | daltons |
Protein Binding | 97 | % |
VD | 0.14 | l/Kg |
pKa | 8.75 | - |
T½ | 9 - 11 / 45 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2012 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is a semisynthetic lipopeptide compound (echinocandin) with antifungal properties used in the treatment of invasive aspergillosis and esophageal candidiasis. Intravenous administration.
At the date of the last update, we found no published data on its excretion in breast milk.
Its pharmacokinetic data (very high percentage of protein binding and high molecular weight) make it highly unlikely that significant quantities will pass into breast milk.
Its low oral bioavailability minimizes the passage into plasma of the infant from ingested breast milk, except in the premature and in the immediate neonatal period in which there may be greater intestinal permeability.