Last update Jan. 29, 2017
Compatible
We do not have alternatives for C19H15NNa2O7 since it is relatively safe.
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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C19H15NNa2O7 is Nedocromil Sodium in Molecular formula.
Is written in other languages:C19H15NNa2O7 belongs to these groups or families:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | < 10 | % |
Molecular weight | 415 | daltons |
Protein Binding | 89 | % |
Tmax | 0.5 | hours |
T½ | 1 - 3.3 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by Academy of Breastfeeding Medicine - 2015 of United States of America
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
It is administered by inhalation for prevention of asthma and atopic rhinitis and as eye drops for allergic conjunctivitis.
At latest update relevant published data on excretion into breast milk were not found.
Pharmacokinetic data (very low bioavailability after inhalation, orally or ophthalmic application with very low plasma levels achieved, moderately elevated molecular weight and a high protein-binding capacity) would render it rather unlikely a significant passage into breastmilk, which would also cause a poor absorption through the infant’s gut .
It is a well tolerated drug with indeed no side effects and none of them reportedly to be serious.
The small dose used and low plasma absorption of most inhaled preparations (either buccal or nasal), topically apply as ophthalmologic or dermatologic preparations, make it unlikely any passage in a significant amount into breastmilk.