Last update Nov. 5, 2024
Compatible
Suggestions made at e-lactancia are done by APILAM team of health professionals, and are based on updated scientific publications. It is not intended to replace the relationship you have with your doctor but to compound it. The pharmaceutical industry contraindicates breastfeeding, mistakenly and without scientific reasons, in most of the drug data sheets.
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Nedocromil Sodium in other languages or writings:
Nedocromil Sodium belongs to these groups or families:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | oral 3. Inhal10 | % |
Molecular weight | 415 | daltons |
Protein Binding | 89 | % |
pKa | 2.2 | - |
Tmax | 0.5 | hours |
T½ | 1 - 3.3 | hours |
Write us at elactancia.org@gmail.com
e-lactancia is a resource recommended by La Liga de la Leche, España of Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM
Nedocromil sodium is a pyranoquinoline with stabilizing action on mast cells similar to that of cromoglycate sodium. It is administered by inhalation for the prevention of asthma and atopic rhinitis and in the form of eye drops for allergic conjunctivitis.
At the time of the last update, we found no published data on its excretion in breast milk.
Its pharmacokinetic data (very low inhaled, oral and ophthalmic bioavailability with very low plasma levels, moderately high molecular weight and high percentage of protein binding) make it very unlikely that significant amounts will pass into milk, which would also be poorly absorbed by the infant.
It is a well-tolerated drug and has practically no side effects, none of them serious.
The small dose and the low plasma absorption of most inhaled (buccal or nasal), ophthalmologic or topical dermatologic preparations make the passage of significant amounts into breast milk unlikely.