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Antibacterial glycopeptide drug.
A high molecular weight its a reason to be excreted in clinically non-significant amount into breast milk, much lower than the dose commonly used for infection in newborns and infants.
Its low oral bioavailability hinders the passage toward infant’s plasma from ingested mother’s milk, except in preterm infants and immediate neonatal period, in which the infant may have an increased intestinal permeability.
Take into account the possibility of negative results of bacterial cultures from febrile infants when their mothers are receiving antibiotics.