Last update: June 15, 2019
Not risky for breastfeeding or infant.
Antiprotozoal and antibacterial (anerobic bacteria). Indicated in urogenital trichomoniasis, nonspecific vaginitis, giardiasis, intestinal and hepatic amebiasis, acute ulcerative gingivitis and prophylaxis of postoperative infections by anaerobic bacteria.
Administered orally or intravenously in a single or daily dose for 3 to 6 days according to pathology.
It is excreted into breast milk in clinically non-significant amount (Evaldson 1985, Männistö 1983, Wood 1982) which is much lower than the dose that is prescribed to infants.
This medication is authorized for use in infants older than 1 month of age.
Some authors recommend waiting 72 hours after the last dose before restarting breastfeeding (CDC 2010, Evaldson 1985). Meanwhile, express and discard breastmilk regularly.
Be aware of false negative results of bacterial cultures obtained from febrile infants whose mothers are on antibiotics, as well as the possibility of gastroenteritis due to altered intestinal flora (Ito 1993).
When topically used with creams and vaginal ovules, absorption into serum is scanty, hence, excretion into breast milk is believed lower than that attained by systemic administration.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.
Thank you for helping to protect and promote breastfeeding.
e-lactancia is a resource recommended by Instituto de Salud Infantil, Grecia-Institute of Child's Health in Greece
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM