Last update: Feb. 15, 2016

Rupatadine Fumarate

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

Second generation antihistamine and piperidine-type compound, without the sedative and anticholinergic effects of first generation antihistaminics.

Pharmacokinetic data (moderately high molecular weight and high percentage of protein binding) make it unlikely an excretion into breast milk in significant amounts.

Until more published data on this drug regarding breastfeeding is available, safer alternatives of better known drugs should be preferable, especially during the neonatal period and in case of prematurity.

Follow-up the baby for drowsiness and inappropriate infant feeding.

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Rupatadine Fumarate in other languages or writings:

Group

Rupatadine Fumarate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Rupatadine Fumarate in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 45 %
Molecular weight 532 daltons
Protein Binding 99 %
Tmax 0,75 hours
T1/2 5,9 hours

References

  1. AEMPS. Rupatadina. Ficha técnica. 2015 Full text (in our servers)
  2. So M, Bozzo P, Inoue M, Einarson A. Safety of antihistamines during pregnancy and lactation. Can Fam Physician. 2010 May;56(5):427-9. Abstract Full text (link to original source) Full text (in our servers)

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