Last update: Dec. 8, 2017


Low Risk for breastfeeding

Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

An Fc-peptide fusion protein that acts as an agonist in the thrombopoietin receptor stimulating platelet production.
Indicated in the treatment of chronic immune thrombocytopenic purpura (ITP) when resistant to other treatments (corticoids, immunoglobulins).
Administered subcutaneously once a week.

Since the last update, we have not found published data on its excretion in breast milk.

Its very high molecular weight makes it very unlikely that it will transfer to milk in significant quantities.

Due to its protein nature it is inactivated in the gastrointestinal tract, not being absorbed, so that its oral bioavailability is practically nil, except in premature babies and the immediate neonatal period when there may be greater intestinal permeability.


We do not have alternatives for Romiplostim.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.


Romiplostim belongs to this group or family:


Main tradenames from several countries containing Romiplostim in its composition:


Variable Value Unit
Oral Bioavail. Baja - Poor %
Molecular weight 59.000 daltons
VD 0,05 - 0,1 l/Kg
Tmax 14 (7 - 50) hours
T1/2 84 (24 - 840) hours


  1. EMA. Romiplostim (Nplate). Drug Summary. 2017 Full text (in our servers)
  2. EMA. Romiplostim (Nplate) Ficha técnica. 2017 Full text (in our servers)

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