Last update: Aug. 17, 2019
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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Thank you for helping to protect and promote breastfeeding.
Rizatriptan Benzoate in other languages or writings:
Main tradenames from several countries containing Rizatriptan Benzoate in its composition:
Variable | Value | Unit |
---|---|---|
Oral Bioavail. | 40 - 45 | % |
Molecular weight | 392 | daltons |
Protein Binding | 14 | % |
VD | 1,8 | l/Kg |
pKa | 9,56 | - |
Tmax | 1 - 2,5 | hours |
T1/2 | 1,6 - 3 | hours |
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e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America
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Selective agonist for the vascular receptor of 5-hydroxytryptamine-1 (5-HT1, serotonin) with vasoconstrictor action at the intracranial level.
Indicated in acute migraine attack.
Oral administration in a daily dose.
Since the last update we have not found published data on its excretion in breastmilk.
Several expert authors consider its use to be safe or probably safe during breastfeeding (Hale 2019, Briggs 2017, Amundsen 2015, Duong 2010).
Its use, usually in isolated doses, makes the occurrence of adverse effects in infants unlikely (Jürgens 2009).
As there is less published data than for other drugs in the same group, safer known alternatives may be preferable, especially during the neonatal period and in cases of prematurity.