Last update: May 1, 2016

Quetiapine Fumarate

Very Low Risk for breastfeeding

Not risky for breastfeeding or infant.

It is excreted into breast milk in clinically significant amount. Clinical or development problems in infants whose mothers were treated have not been observed, whether at the short or long term.
Very low plasma-levels in these infants were found.

Galactorrhea may occur with or without an increased of Prolactin.


We do not have alternatives for Quetiapine Fumarate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Quetiapine Fumarate in other languages or writings:


Quetiapine Fumarate belongs to this group or family:


Main tradenames from several countries containing Quetiapine Fumarate in its composition:


Variable Value Unit
Bioavailability 10 %
Molecular weight 883 daltons
Protein Binding 83 %
VD 10 l/Kg
Tmax 1,5 hours
T1/2 7 hours
M/P ratio 0,3 -
Theoretical Dose 0,01 - 0,1 mg/Kg/d
Relative Dose 0,1 - 0,43 %


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  2. Grover S, Avasthi A. Mood stabilizers in pregnancy and lactation. Indian J Psychiatry. 2015 Abstract Full text (link to original source) Full text (in our servers)
  3. Aydin B, Nayir T, Sahin S, Yildiz A. Olanzapine and quetiapine use during breastfeeding: excretion into breast milk and safe breastfeeding strategy. J Clin Psychopharmacol. 2015 Abstract
  4. Van Boekholt AA, Hartong EG, Huntjens-Fleuren H, Grootens KP, Semmekrot BA. Quetiapine concentrations during exclusive breastfeeding and maternal quetiapine use. Ann Pharmacother. 2015 Abstract
  5. Larsen ER, Damkier P, Pedersen LH, Fenger-Gron J, Mikkelsen RL, Nielsen RE, Linde VJ, Knudsen HE, Skaarup L, Videbech P. Use of psychotropic drugs during pregnancy and breast-feeding. Acta Psychiatr Scand Suppl. 2015 Abstract
  6. Parikh T, Goyal D, Scarff JR, Lippmann S. Antipsychotic drugs and safety concerns for breast-feeding infants. South Med J. 2014 Abstract
  7. Rowe H, Baker T, Hale TW. Maternal medication, drug use, and breastfeeding. Pediatr Clin North Am. 2013 Feb;60(1):275-94. Abstract
  8. Suttajit S, Srisurapanont M, Xia J, Suttajit S, Maneeton B, Maneeton N. Quetiapine versus typical antipsychotic medications for schizophrenia. Cochrane Database Syst Rev. 2013 Abstract
  9. Klinger G, Stahl B, Fusar-Poli P, Merlob P. Antipsychotic drugs and breastfeeding. Pediatr Endocrinol Rev. 2013 Abstract
  10. Mushtaq S, Khan S, Patel H. Quetiapine-induced galactorrhea with normal prolactin level in an adult female patient. Prim Care Companion CNS Disord. 2012 Abstract Full text (in our servers)
  11. Davanzo R, Copertino M, De Cunto A, Minen F, Amaddeo A. Antidepressant drugs and breastfeeding: a review of the literature. Breastfeed Med. 2011 Abstract
  12. Sethi S, Sharma M, Malik A. Dose-dependent galactorrhea with quetiapine. Indian J Psychiatry. 2010 Abstract
  13. Juruena MF, de Sena EP, de Oliveira IR. Safety and tolerability of antipsychotics: focus on amisulpride. Drug Healthc Patient Saf. 2010 Abstract Full text (link to original source) Full text (in our servers)
  14. Newport DJ, Ritchie JC, Knight BT, Glover BA, Zach EB, Stowe ZN. Venlafaxine in human breast milk and nursing infant plasma: determination of exposure. J Clin Psychiatry. 2009 Abstract
  15. Schlotterbeck P, Leube D, Kircher T, Hiemke C, Gründer G. Aripiprazole in human milk. Int J Neuropsychopharmacol. 2007 Abstract Full text (in our servers)
  16. Gupta M. Low dose quetiapine induced galactorrhoea: a case report. Clin Pract Epidemiol Ment Health. 2007 Abstract
  17. Klier CM, Mossaheb N, Saria A, Schloegelhofer M, Zernig G. Pharmacokinetics and elimination of quetiapine, venlafaxine, and trazodone during pregnancy and postpartum. J Clin Psychopharmacol. 2007 Abstract
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  19. Misri S, Corral M, Wardrop AA, Kendrick K. Quetiapine augmentation in lactation: a series of case reports. J Clin Psychopharmacol. 2006 Abstract
  20. Gentile S. Prophylactic treatment of bipolar disorder in pregnancy and breastfeeding: focus on emerging mood stabilizers. Bipolar Disord. 2006 Abstract
  21. Gentile S. Quetiapine-fluvoxamine combination during pregnancy and while breastfeeding. Arch Womens Ment Health. 2006 Abstract
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  23. Gentile S. Clinical utilization of atypical antipsychotics in pregnancy and lactation. Ann Pharmacother. 2004 Abstract
  24. Atmaca M, Kuloglu M, Tezcan E, Canatan H, Gecici O. Quetiapine is not associated with increase in prolactin secretion in contrast to haloperidol. Arch Med Res. 2002 Abstract

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