Last update: May 27, 2018
Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
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Anti-epileptic drug with structural properties similar to Gabapentin. Also used in the treatment of anxiety disorders, neuropathic pain and fibromyalgia.
Oral administration in two - three daily doses.
It is excreted in breast milk in small amounts, probably not clinically significant (Lockwood 2016).
In a mother who took it during pregnancy, very high milk levels were found at 48 hours after birth, probably due to a transplacental passage (Ohman 2011).
No side effects were observed in the infant (Ohman 2011).
Slight difficulty of breastfeeding has been reported in 7% of newborns of mothers who were given a dose of pregabalin prior to cesarean section (El Kenany 2016).
Several authors and experts agree that the use of this medication is safe during lactation, monitoring possible side effects (drowsiness) in the infant (Crettenand 2018, Reece 2017, Davanzo 2013).
Because less experience has been published than with other drugs of the same group, alternatives that are known as safer should be considered of choice during the neonatal period or in case of preterm babies.
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
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