Last update: Feb. 7, 2020

Polycystic Ovary Syndrome

Very Low Risk for breastfeeding

Safe. Compatible.
Minimal risk for breastfeeding and infant.

Polycystic Ovary Syndrome (PCOS) is a disorder caused by sexual hormone dysfunction that can lead to problems like infertility, overweight, obesity, breast hypoplasia, gestacional induced diabetes and higher abortion risk (Biloš 2017, Goldenberg 2008).

Although it is controversial (Biloš 2017, Thatcher 2006, Marasco 2000), breastfeeding may be seriously affected (20% of failure after some authors) especially if mammary gland hypoplasia or absence of breast enlargement during pregnancy occurs (Biloš 2017, McGuire 2015, Vanky 2012, Marasco 2000). Obesity and gestacional Diabetes also may affect breastfeeding (Biloš 2017, Riddle 2016). One factor possibly implicated in the low milk supply observed is insulin resistance (Biloš 2017).

Both disease and medication used for treatment are compatible with breastfeeding (Lawrence 2013). Fighting overweight by means of a hypocaloric diet and physical exercise is most important to improve symptoms of disease.

Merformin helps to control Overweight and Diabetes and also ameliorate other symptoms of disease (Cicero 2012, Goldenberg 2008, Glueck 2007, Thatcher 2006) and it is compatible with breastfeeding (Glueck 2007 & 2006), but has not been shown to improve milk production.

An appropriate breastfeeding technique with frequent feedings, milk expression by the use of pump if required to increase stimulus beside with the use of galactogogues like Domperidone may enhance milk production. If necessary, supplementation with banked milk or artificial formula would be indicated.

See below the information of these related products:

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

Polycystic Ovary Syndrome is also known as


Polycystic Ovary Syndrome belongs to this group or family:


  1. Biloš LSK. Polycystic ovarian syndrome and low milk supply: Is insulin resistance the missing link? Endocr Oncol Metab 2017; Vol 3 (2):49-55 2017 Full text (link to original source) Full text (in our servers)
  2. Riddle SW, Nommsen-Rivers LA. A Case Control Study of Diabetes During Pregnancy and Low Milk Supply. Breastfeed Med. 2016 Abstract Full text (link to original source) Full text (in our servers)
  3. McGuire E, Rowan MK. PCOS, breast hypoplasia and low milk supply: A case study. Breastfeed Rev. 2015 Abstract
  4. Lawrence RM. Circumstances when breastfeeding is contraindicated. Pediatr Clin North Am. 2013 Feb;60(1):295-318. Abstract
  5. Cicero AF, Tartagni E, Ertek S. Metformin and its clinical use: new insights for an old drug in clinical practice. Arch Med Sci. 2012 Abstract Full text (link to original source) Full text (in our servers)
  6. Vanky E, Nordskar JJ, Leithe H, Hjorth-Hansen AK, Martinussen M, Carlsen SM. Breast size increment during pregnancy and breastfeeding in mothers with polycystic ovary syndrome: a follow-up study of a randomised controlled trial on metformin versus placebo. BJOG. 2012 Abstract Full text (link to original source) Full text (in our servers)
  7. Goldenberg N, Glueck C. Medical therapy in women with polycystic ovarian syndrome before and during pregnancy and lactation. Minerva Ginecol. 2008 Abstract
  8. Glueck CJ, Wang P. Metformin before and during pregnancy and lactation in polycystic ovary syndrome. Expert Opin Drug Saf. 2007 Abstract
  9. Thatcher SS, Jackson EM. Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin. Fertil Steril. 2006 Abstract
  10. Glueck CJ, Salehi M, Sieve L, Wang P. Growth, motor, and social development in breast- and formula-fed infants of metformin-treated women with polycystic ovary syndrome. J Pediatr. 2006 Abstract
  11. Marasco L, Marmet C, Shell E. Polycystic ovary syndrome: a connection to insufficient milk supply? J Hum Lact. 2000 Abstract

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