Last update: Dec. 1, 2004

Pizotifen

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

It is a first generation antihistaminic and piperidine drug with a moderately sedative effect. Minimally secreted into breast milk. Indicated for anorexia (Cyproheptadine is safer) and long-term prophylaxis of migraine (Propranolol or Valproate are considered to be safer drugs)

Alternatives

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

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Other names

Pizotifen is also known as


Group

Pizotifen belongs to this group or family:

Tradenames

Main tradenames from several countries containing Pizotifen in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. Alta - Hig %
Molecular weight 295 daltons
Protein Binding 90 %
Tmax 5 hours
T1/2 23 hours

References

  1. Davanzo R, Bua J, Paloni G, Facchina G. Breastfeeding and migraine drugs. Eur J Clin Pharmacol. 2014 Abstract

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