Last update: April 17, 2016

ピナベリウムブロミド

Low Risk for breastfeeding


Moderately safe. Probably compatible.
Mild risk possible. Follow up recommended.
Read the Comment.

A Calcium channel blocker with spasmolytic activity on the intestine and antimuscarinic effects.

At latest update no published data were found on excretion into breast milk.
Pharmacokinetic data (moderately high molecular weight and high protein binding) make unlikely the passage into milk in significant amounts.
Its low oral bioavailability hinders its passage into infant's plasma from ingested milk, except in preterm infants and immediate neonatal period, since they may exhibit an increased intestinal permeability.

Anticholinergics may reduce milk production: take a minimum necessary dose and avoid prolonged treatment if decreased milk is observed.

Alternatives

We do not have alternatives for ピナベリウムブロミド.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Other names

ピナベリウムブロミド is Pinaverium Bromide in Japanese.

Is written in other languages:

Group

ピナベリウムブロミド belongs to this group or family:

Tradenames

Main tradenames from several countries containing ピナベリウムブロミド in its composition:

Pharmacokinetics

Variable Value Unit
Oral Bioavail. 1 %
Molecular weight 591 daltons
Protein Binding 97 %
Tmax 1 hours
T1/2 1,5 hours

References

  1. BGP. Pinaverium. Product Monograph. 2015 Full text (in our servers)
  2. Annaházi A, Róka R, Rosztóczy A, Wittmann T. Role of antispasmodics in the treatment of irritable bowel syndrome. World J Gastroenterol. 2014 Abstract
  3. AEMPS. Pinaverio. Ficha técnica. 2014 Full text (in our servers)

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