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An antiprotozoal used in the treatment of cryptosporidiosis, giardiasis, intestinal amebiasis, blastocystosis, cutaneous leishmaniasis and microsporidiosis.
Oral administration twice a day for 3 days.
Its pharmacokinetic data - extremely high percentage of protein binding (MK 2014, FDA 2005) and short half-life (Stocks 1996) - explain the negligible transfer to breastmilk observed (Hadad 2012).
Its use is authorized in children from one year of age (Committee 2015, FDA 2005).
Possible side effects are not frequent or serious (abdominal pain, diarrhea, vomiting, headache).
Several experts consider its use to be safe during breastfeeding (Hale 2017 p 710, Briggs 2017, Lactmed 2013).