Last update: Jan. 29, 2014

Oseltamivir Phosphate

Very Low Risk for breastfeeding


Compatible.
Not risky for breastfeeding or infant.

Prophylaxis and treament of Influenza virus disease.

Excreted in non-significant levels into breast milk. No adverse effects have been shown in breastfed infants.

Alternatives

We do not have alternatives for Oseltamivir Phosphate since it is relatively safe.

Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.

Jose Maria Paricio, Founder & President of APILAM/e-Lactancia

Your contribution is essential for this service to continue to exist. We need the generosity of people like you who believe in the benefits of breastfeeding.

Thank you for helping to protect and promote breastfeeding.

José María Paricio, founder of e-lactancia.

Group

Oseltamivir Phosphate belongs to this group or family:

Tradenames

Main tradenames from several countries containing Oseltamivir Phosphate in its composition:

Pharmacokinetics

Variable Value Unit
Bioavailability 75 %
Molecular weight 410 daltons
Protein Binding 42 %
VD 0,38 l/Kg
T1/2 6 - 10 hours
Theoretical Dose 0,012 mg/Kg/d
Relative Dose 0,6 %
Relat.Ped.Dose 0,3 - 0,6 %

References

  1. Greer LG, Leff RD, Rogers VL, Roberts SW, McCracken GH Jr, Wendel GD Jr, Sheffield JS. Pharmacokinetics of oseltamivir in breast milk and maternal plasma. Am J Obstet Gynecol. 2011 Abstract Full text (in our servers)
  2. Dembinski J. [Oseltamivir in pregnancy, lactation and neonatal period--comparison of international recommendations]. Z Geburtshilfe Neonatol. 2010 Abstract
  3. Skalli S, Ferreira E, Bussières JF, Allenet B. [Influenza A/H1N1v 2009 during pregnancy and breastfeeding: which antiviral to choose?]. Ann Pharm Fr. 2010 Abstract
  4. Chen LH, Zeind C, Mackell S, LaPointe T, Mutsch M, Wilson ME. Breastfeeding travelers: precautions and recommendations. J Travel Med. 2010 Jan-Feb;17(1):32-47. Abstract Full text (link to original source) Full text (in our servers)
  5. Tanaka T, Nakajima K, Murashima A, Garcia-Bournissen F, Koren G, Ito S. Safety of neuraminidase inhibitors against novel influenza A (H1N1) in pregnant and breastfeeding women. CMAJ. 2009 Abstract Full text (in our servers)
  6. Academy of Breastfeeding Medicine. Breastfeeding / Swine Flu Recommendations for Physicians from the Academy of Breastfeeding Medicine For immediate release (ABM) 2009 Full text (in our servers)
  7. Agencia Europea del Medicamento (EMA) Oseltamivir Ficha técnica 2009 Full text (in our servers)
  8. Agencia Española del Medicamento Uso de Oseltamivir y Zanamivir en niños de cualquier edad, en mujeres gestantes y mujeres en periodo de lactancia y en personas con problemas de deglución. \ Nota Informativa 2009 Full text (in our servers)
  9. Wentges-van Holthe N, van Eijkeren M, van der Laan JW. Oseltamivir and breastfeeding. Int J Infect Dis. 2008 Abstract Full text (in our servers)

Total visits

20,721

Help us improve this entry

How to cite this entry

Do you need more information or did not found what you were looking for?

   Write to us at elactancia.org@gmail.com

e-lactancia is a resource recommended by Academy of Breastfeeding Medicine from United States of America

Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM