Last update: Nov. 23, 2019
Minimal risk for breastfeeding and infant.
An autosomal recessive congenital disease in which there is an enzymatic deficit that prevents the metabolization of the essential amino acid phenylalanine to the amino acid tyrosine, producing an accumulation of phenylalanine in the body that, untreated, damages the central nervous system causing mental deficiency.
The treatment consists of restricting from one’s diet foods that contain large amounts of phenylalanine, especially pulses, soya beans, meat, fish, eggs, cereals (except rice and corn), dairy products and the sweetener aspartame.
This restriction, which is fundamental in the initial stage of life, is recommended to be life-long.
During pregnancy, women with phenylketonuria should have stricter control of their phenylalaninemia levels through diet in order to prevent embryopathy syndrome due to phenylalanine in their babies (Manta 2018, MotherToBaby 2017 and 2015, Lawrence 2016 p.591, Murphy 2015, Purnell 2001, Campistol 1999, Matalon 1986, Bradburn 1985).
Mothers with phenylketonuria breastfed their healthy children without problems (Purnell 2001, Fox-Bacon 1997, Matalon 1986, Bradburn 1985).
Milk from mothers with phenylketonuria controlled by diet has normal levels of phenylalanine (Matalon 1986).
Breastfeeding mothers suffering from phenylketonuria can breastfeed their healthy babies without problems, who are not affected by phenylketonuria (MotherToBaby 2017 and 2015, Lawrence 2016 p.591, Lawrence 2013, Purnell 2001, Matalon 1986).
There is little or no relationship between plasma levels of phenylalanine and those of prolactin in patients who have the illness under control (Juhász 2016, Carlson 1992).
Suggestions made at e-lactancia are done by APILAM´s pediatricians and pharmacists, and are based on updated scientific publications.
It is not intended to replace the relationship you have with your doctor but to compound it.
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e-lactancia is a resource recommended by Asociación Española de Bancos de Leche Humana from Spain
Would you like to recommend the use of e-lactancia? Write to us at corporate mail of APILAM